by Dr. Ed Weber | Feb 14, 2023 | PCa Commentary
The set-point for biochemical failure was standardized in 2006 based on a consensus conference of experts in Phoenix, Arizona. The value agreed upon was “PSA + 2 ng/mL above the post-radiation PSA nadir — hence the “Phoenix Definition.” (Roach et...
by Dr. Ed Weber | Dec 28, 2022 | PCa Commentary
Metastases Directed Therapy refers to targeted radiation, i.e., such as CyberKnife, directed at a few metastatic lesions, (osseous or nodal), usually 3 – 5, for the purpose of controlling all imageable disease, delaying cancer progression and, if not accompanied...
by Dr. Ed Weber | Nov 8, 2022 | PCa Commentary
Nonmetastatic castration-resistant prostate cancer (nmCRPC) is a transient, heterogeneous state that progresses to metastatic disease. nmCRPC is defined as a rising PSA after primary therapy in association with a castrate level of testosterone (<50 ng/mL) while...
by Dr. Ed Weber | Oct 25, 2022 | PCa Commentary
The key to optimal outcomes in active surveillance is careful patient selection and monitoring of participants during AS. MRI guided biopsy at initial diagnosis: Lee et al., Korean J Radiol. 2021 Jul, argue that in men in whom there is a clinical suspicion of prostate...
by Dr. Ed Weber | Sep 21, 2022 | PCa Commentary
Any man diagnosed with prostate cancer is likely aware that lowering testosterone (T) levels achieves control of the cancer at various stages of the disease. Question: What is the underlying biology and function of that therapeutic maneuver (androgen deprivation...
