Compare Prostate Cancer Treatments – High Risk

Who Remained Prostate Cancer Free?

High Risk prostate cancer patients experience the highest range of results and approaches as they are likely to have prostate cancer outside of the prostate. When selecting a course of action, consultations are recommended with a urologist or surgeon, radiation oncologist and medical oncologist. Different treatments have different results and side effects. It is important to understand the potential impact each treatment can have on your quality of life after treatment.

For High Risk prostate cancer patients, the possibility of prostate cancer relapse increases. Relapse or recurrence, happens when the cancer returns, and may result in additional treatment. To understand how effective the treatment or combination of treatments are in keeping patients in remission, Doctors perform periodic monitoring or testing PSA levels following treatment.  It is very unlikely that the cancer will ever return, if you remain in remission for 10-15 years after prostate cancer treatment. Click on 'Get the Study', to obtain your copy of Foundation's work. Discuss this with your Doctor as you choose a treatment plan.

High Risk is any of the following:

PSA greater than 20

Gleason Score is 8 to 10

Clinical Stage is T2c to T3c

  Hypo EBRT

Compare Treatments for other Risk Groups


How to Use the Graph
Add or remove treatment options above, using the checkboxes, for example Surgery vs Seeds. Percent PSA Progression Free is represented by the the vertical axis. The bottom axis of the graph tracking time in years, in this case up to 16 years. Circles, triangles, diamonds or squares on the graph each represent a treatment study with a different number of patients. The midpoint of the ellipse shows on average how the patients responded to a that treatment. The direction of the ellipse, shows how the patients trended over time.

Learn More About How these Charts Work

About the Data
Percent PSA Progression Free control results are the most sensitive means to measure initial treatment success and are used in these comparisons. A PSA Progression Free of 100% would mean that for all patients, the cancer has not returned, and no follow up treatment was necessary. These graphs are cancer control probabilities and not survival graphs. Survival in all groups is high regardless of treatment, as patients can often live for years despite failure of the initial treatment. Cancer control is the focus of this analysis. The longer a treatment can maintain a PSA Progression Free close to 100%, the more effective the Treatment. Each treatment ellipse is mathematically calculated to help you visualize how the patients are doing with the selected treatment.

For More Information:

Compare Prostate Cancer Treatment Tutorial

This tutorial will lead you through the process of comparing prostate cancer treatment outcomes across low, intermediate and high risk patients. The treatments included in this study are Prostate Surgery or Prostatectomy, (Retropubic, Laparoscopic, and Robotic), Brachytherapy or Seeds, High Dose Rate Radiation, HDR, External Beam Radiation Therapy or EBRT, Androgen Deprivation Therapy, ADT, or Hormone Treatment, Proton Therapy, High-Intensity Focused Ultrasound, HIFU, Cryotherapy, Cryo and Hypo-Fractionated External Beam Radiation Therapy. For more advanced prostate cancer, treatments are combined to increase effectiveness. 

Remission versus Recurrence?

Relapse of prostate cancer is way more common than you might think. Many men treated for prostate cancer have their cancer return, which can lead to a lifetime of treatment. Prostate Cancer Free studies treatment outcomes documented in "The STUDY", recently updated for 2021. Take this Study to your doctor, and discuss your chance of cancer recurrence. The Study is available with the new, just released booklet, to help you learn about prostate cancer. Both the Prostate Cancer Free Study and the booklet, “What You Need to Know About Prostate Cancer” are available NOW for you to VIEW, PRINT or DOWNLOAD.

Get The Study

Help To Continue the Work!

The Prostate Cancer Free Foundation, reviews the results of hundreds of thousands of men treated for prostate cancer. Tracking them for years. This information is available to you, and others like you, to help find the best prostate cancer treatment. This work takes time, effort, resources all of it done by volunteers. Please help us continue. Please Donate!